| Parent Term | Preferred Term | Definition | Definition Source | Alternative Term | AlternativeTermSource |
|---|---|---|---|---|---|
| Silencing RNA Reagent Type | siRNA | Small RNAs of 21–23 nucleotides in length that engage the complementary mRNA into the RISC complex for degradation | PMID: 16607417 | small interfering RNA | |
| Silencing RNA Reagent Type | shRNA | Small dsRNA constructs that are usually 22–29 nucleotides long and form a hairpin-like secondary structure | PMID: 16607418 | short hairpin RNA | |
| siRNA | esiRNA | Mixture of siRNA oligos resulting from cleavage of long double-stranded RNA (dsRNA) with Escherichia coli RNase III | http://www.ncbi.nlm.nih.gov/projects/genome/probe/doc/Glossary.shtml/ | Endoribonuclease-prepared siRNAs | |
| Silencing RNA Reagent Type | stRNA | stRNAs exert negative post-transcriptional regulation by binding to complementary sequences in the 3' untranslated regions of their target genes. stRNAs are transcribed as longer precursor RNAs that are processed by the RNase Dicer/DCR-1 and members of the RDE-1/AGO1 family of proteins. | http://www.ncbi.nlm.nih.gov/projects/genome/probe/doc/Glossary.shtml | Small temporal RNA | |
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